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Yes, the locked file message should come from AxCrypt. It’s AxCrypt who tries to open the file – and finds that it’s locked for sharing, and then displays the message in question.
I sincerely doubt that the cause of these issues is the standalone AxCrypt software as such. It’s just a single .NET executable, running without any special permissions, and doing nothing special. No, it does not write the registry.
If you kill the software with Task Manager (it should really just be easy to kill) or for that matter reboot and don’t start it, it does not and cannot affect your system in anyway. It’s just a passive file sitting in your file system. It can’t do anything unless you click it to run. No matter how problematic it could be – if it’s not running it can’t do anything to your system.
Do ensure that the software you’re getting comes directly from https://www.axcrypt.net/ and no-where else, and that the digital signature by AxCrypt AB is correct.